Elab Fluor® 647 Anti-Human CD127/IL-7RA Antibody [A019D5]

Sizes: 20 Tests, 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1152M-20, E-AB-F1152M-100, E-AB-F1152M-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD127/IL-7RA

Target Synonym: Interleukin-7 receptor subunit alpha, IL-7RA, CDw127, CD127, IL-7Rα,

Conjugation: Elab Fluor® 647

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Mouse IgG1, κ

Clone No.: A019D5

UNIProt ID: P16871

Background: CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09792M

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 3575

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only