Benzyl-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1027926-86-8

Molecular Weight: 368.46

Formula: C20H32O6

Chemical Name: 2-[(1-phenyl-2,5,8,11-tetraoxatridecan-13-yl)oxy]oxane

Smiles: C(OCCOCCOCCOCCOC1CCCCO1)C1C=CC=CC=1

InChiKey: KNXMANKMVQASTE-UHFFFAOYSA-N

InChi: InChI=1S/C20H32O6/c1-2-6-19(7-3-1)18-24-15-14-22-11-10-21-12-13-23-16-17-26-20-8-4-5-9-25-20/h1-3,6-7,20H,4-5,8-18H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.